Month: December 2016
More progress on huntingtin cryo-EM
I was over the moon last week to receive an update (available here) on the cryo-electron microscopy grid preparation from Dr Justin Deme, a post doc in Prof Susan Lea’s lab. Using the full-length huntingtin protein samples I prepared, Justin is preparing very small grids with the protein on them so that we can look Read More …
Updates on huntingtin EM and domain construct test expression
Last week was all about big protein samples! I got an informative email update from Prof Susan Lea and Dr Justin Deme on the full-length huntingtin EM work (all 3144 amino acids) they are doing in Oxford. The grids are definitely getting better and hopefully we will have thin enough ice to do some serious Read More …