
Month: December 2017
Huntingtin sample preparation before the holidays
Before the university shuts down for the holidays, I have been busy in the lab making huntingtin protein samples. I purified wild-type huntingtin with a polyQ stretch of Q23 as well as disease versions of the protein with Q54 and Q145. Whilst Q23 huntingtin protein can be trivially expressed and purified, the longer polyQ length Read More …